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The Yun lab

Regeneration of complex structures in adult vertebrates

 

Research Outlook

Humans exhibit rather limited capabilities for tissue repair and regeneration. In contrast, organisms with remarkable regenerative abilities can be found in nature. Among these, salamanders (such as newts and axolotls) are considered the champions of regeneration, being able to regrow an extraordinary range of complex structures including ocular tissues, tail, jaws, large sections of their heart, parts of their nervous system, and entire limbs throughout their life. As such, the salamander constitutes an ideal system in which to learn how accurate regeneration of body structures can be achieved.
Our lab aims to exploit this system in order to unveil the cellular and molecular mechanisms underlying organ regeneration, determine how phylogenetic changes affect regenerative potential, and probe the link between regeneration and ageing. 

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Funding

Alexander von Humboldt Stiftung

CRTD-Center for Regenerative Therapies TU Dresden

DAAD - German Academic Exchange Service

Deutsche Forschungsgemeinschaft

DIGS-BB

Fulbright

Technische Universität Dresden

MWRF

 

Contact Us

Our Lab is affiliated to CRTD- Center for Regenerative Therapies TU Dresden &
Max Planck Institute of Molecular Cellular Biology and Genetics &
PoL - Physics of Life Excellence Cluster Dresden

Visitor Address:
CRTD / TU Dresden
Fetscherstrasse 105
01307 Dresden

+49 351 458-82022

https://tu-dresden.de/cmcb/crtd

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