The Yun lab
Regeneration of complex structures in adult vertebrates
Humans exhibit rather limited capabilities for tissue repair and regeneration. In contrast, organisms with remarkable regenerative abilities can be found in nature. Among these, salamanders (such as newts and axolotls) are considered the champions of regeneration, being able to regrow an extraordinary range of complex structures including ocular tissues, tail, jaws, large sections of their heart, parts of their nervous system, and entire limbs throughout their life. As such, the salamander constitutes an ideal system in which to learn how accurate regeneration of body structures can be achieved.
Our lab aims to exploit this system in order to unveil the cellular and molecular mechanisms underlying organ regeneration, determine how phylogenetic changes affect regenerative potential, and probe the link between regeneration and ageing.
Alexander von Humboldt Stiftung
CRTD-Center for Regenerative Therapies TU Dresden
DAAD - German Academic Exchange Service
Technische Universität Dresden
Our Lab is affiliated to CRTD- Center for Regenerative Therapies TU Dresden &
Max Planck Institute of Molecular Cellular Biology and Genetics &
PoL - Physics of Life Excellence Cluster Dresden
CRTD / TU Dresden
+49 351 458-82022